Montelukast and Nasal Polyposis

    Some medical research indicates that montelukast, an leukotriene receptor antagonists, may retard the growth of polyps in the sinuses and the noses.  As one suffering from such polyps, this is of great interest to me.  I have been taking montelukast in the hopes that it does retard the growth of my polyps, and thus increase the time I can go between surgeries to remove the damn polyps.  I started using montelukast in 2002 and have not needed surgery since then.  I have also not since then needed systemic steroids to keep my sense of smell intact.

• Efficacy of montelukast in the treatment of nasal polyposis --  Ann Otol Rhinol Laryngol. 2005 Dec;114(12):941-5.

• Is There a Role for Leukotriene Antagonists in the Prevention of Recurrent Nasal Polyps? -- Medscape, may need to subscribe (free) to read the article.

• Montelukast as an Adjunct to Oral and Inhaled Steroid Therapy in Chronic Nasal Polyposis

• Oral Antihistamines Alone vs in Combination with Leukotriene Receptor Antagonists for Allergic Rhinitis: A Meta-analysis

• Polyposis nasi--improvement in quality of life by the influence of leukotrien receptor antagonists -- Laryngorhinootologie. 2007 Apr;86(4):282-6. Epub 2007 Feb 8

• Otolaryngology–Head and Neck Surgery -- search the journal for articles of interest on polyposis etc.

• A Bunch of Stuff via Google