Abstract.  Paper analyzes the dynamics of transnational social movement mobilization that in May 2000 forced an American multinational Smithfield Foods, Inc. to abandon its plans to develop large animal confinement facilities in Poland. It is argued that three factors contributed to the success of this cross-national collaboration between coalition of environmental, and family farm groups led by the Animal Welfare Institute in the U.S. and Polish farmers, labor unions, and the Samoobrona organization. The mobilization was facilitated by preexisting social movement organizations, a favorable context of political opportunity, and innovative strategic leadership by the Animal Welfare Institute in coordinating the campaign. Process of transnational coalition building and specific tactics used by anti-corporate activists is analyzed in terms of their effectiveness in thwarting, thus far, Smithfield's efforts to developing large scale concentrated animal feeding operations (CAFO's) in Poland. Implications of the US-Polish activists' success in understanding constraints and opportunities for transnational social movements against neo-liberal policies are discussed.