Slide 35 of 62
Notes:
1) Preinitiation complex formation: 43S
2) Binding of 43S complex with mRNA: uses eIF4A, B, E, G (shown in next slide)
No direct binding to AUG--bound to cap--then scanning to find first AUG
3) Addition of 60S subunit to make 80S initiation complex
eIF2B promotes GTP exchange on eIF2 once AUG is found
