Slide 30 of 62
Notes:
Release factors are not tRNAs but resemble tRNAs; they bind to the termination codon in the A site.
RF-1: Binds UAG, UAA, RF-1 UAA and UGA; RF-3 is GTPase
Instead of catalyzing peptidyl transfer, the transferase hydrolyzed the ester bond linking the peptide with the tRNA (actually transfers the peptide to a water molecule.
